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Linking histopathological changes in intervertebral disc with lumbar muscles strength
Amlesh Kumar Yadav1, Sridevi Nangali Srinivasa1
1Department of Anatomy, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India, 536101.
Bioinformation
|October 30, 2023
Summary
Low back pain is linked to lumbar intervertebral disc degeneration. This degeneration directly increases pain and decreases back muscle strength, as confirmed by MRI and histological analysis.
Area of Science:
- Orthopedics
- Neurology
- Radiology
Background:
- Low back pain (LBP) affects 80% of the population.
- Lumbar intervertebral disc degeneration and reduced muscle force are primary causes of LBP.
Purpose of the Study:
- To investigate the relationship between histological degeneration of the lumbar intervertebral disc and clinical outcomes in patients with LBP.
Main Methods:
- Sixty-two LBP patients undergoing discectomy were analyzed.
- Lumbar muscle strength, visual analogue scale (VAS) for pain, MRI scans, and histological changes were assessed.
Main Results:
- Histological disc degeneration directly correlates with increased lumbar pain.
- Degenerative changes are associated with decreased lumbar flexor and extensor muscle strength.
- MRI findings reflect the observed degenerative changes.
Conclusions:
- Histological disc degeneration is a key factor in LBP severity and associated muscle weakness.
- MRI can visualize degenerative changes linked to LBP.
- Understanding these links aids in managing LBP effectively.
