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Care Cascades for Hypertension in Low-Income Settings: A Systematic Review and Meta-Analysis
Demetrio Lamloum1,2, Federico Fassio3, Brianna Osetinsky4,5
1Department of Preventive, Restorative and Pediatric Dentistry, University of Bern, Bern, Switzerland.
Insights
Hypertension care cascade (HCC) is less effective in low-income countries (LICs). This review shows lower awareness, treatment, and control of high blood pressure in LICs, highlighting the need for tailored interventions.
Area of Science:
- Cardiovascular Disease Epidemiology
- Global Health Interventions
- Health Systems Research
Background:
- High blood pressure is a primary risk factor for cardiovascular disease globally.
- The hypertension care cascade (HCC) framework assesses the continuum of care for hypertension management.
- Evaluating HCC in low-income settings is crucial for improving cardiovascular health outcomes.
Approach:
- Systematic review of studies published between January 2010 and April 2023.
- Inclusion criteria focused on complete HCC data in adult populations, excluding reviews and studies on fragile patients.
- Data extraction and quality assessment using MOOSE guidelines and JBI Critical Appraisal Tools.
Key Points:
- Analyzed 95 articles, revealing an average hypertension prevalence of 33%, with lower rates in low-income countries (LICs) compared to lower-middle-income countries (LMICs).
- Overall hypertension awareness was 48%, treatment 35%, and control 16%, with significantly lower percentages observed in LICs and Sub-Saharan Africa.
- Performance across all stages of the HCC was notably poorer in LICs.
Conclusions:
- Hypertension care cascade performance varies significantly across different countries.
- Low-income settings demonstrate poorer outcomes in hypertension awareness, treatment, and control.
- There is a critical need for developing and implementing interventions specifically designed for low-income settings to enhance hypertension care.
Abstract:
Objective: High blood pressure is the leading risk factor for cardiovascular disease. The hypertension care cascade (HCC) is increasingly being used to evaluate the effectiveness of interventions. This systematic review aims to examine HCC in low-income settings. Methods: The search strategy included articles published between January 2010 and April 2023. We excluded studies with incomplete HCC, on fragile patients or aged <18 years, reviews. We used the MOOSE guideline. Five researchers retrieved data on the survey year, country, population, HCC and diagnostic methods for hypertension. We used JBI Critical Appraisal Tools for quality assessment. Results: Ninety-five articles were analyzed. Average hypertension prevalence was 33% (95% CI: 31%-34%), lower in LICs than in LMICs (25% vs. 34%). The overall mean awareness of hypertension was 48% (95% CI: 45%-51%), its treatment was 35% (95% IC: 32%-38%) and its control 16% (95% CI: 14%-18%). In almost all steps, percentages were lower in LICs and in Sub-Saharan Africa. Conclusion: Trends in HCC vary between countries, with poorer performance in LICs. This review highlights the need for interventions tailored to low-income settings in order to improve hypertension care.
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