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Semi-Autologous Corneal Transplantation with Simultaneous Bilateral Surgery: A Case Report
Nefeli E Kounatidou1, Dimitra Kopsini2, Allister Gibbons3
1Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Case Reports in Ophthalmology
|October 30, 2023
Summary
This case study details a unique semi-autologous corneal transplant using a patient's own eye tissue. Despite initial success, the surgery was complicated by indolent endophthalmitis, leading to graft failure.
Area of Science:
- Ophthalmology
- Transplantation Surgery
Background:
- Corneal transplantation is a common procedure for vision restoration.
- Recurrent graft failure can occur due to various factors, including infection and endothelial cell dysfunction.
Observation:
- An 86-year-old male with a history of six failed corneal grafts underwent a simultaneous bilateral semi-autologous corneal transplantation.
- A clear, 30-year-old graft from the patient's amblyopic left eye was used for the right eye.
Findings:
- The semi-autologous graft initially remained clear, but vitreous cultures revealed coagulase-negative Staphylococcus.
- The patient developed retinal detachment and vision loss in the operated eye, attributed to chronic indolent endophthalmitis.
Implications:
- This case highlights the potential of semi-autologous grafts in managing complex corneal failure cases.
- It underscores the importance of considering indolent endophthalmitis in cases of multiple corneal graft failures.
- Simultaneous bilateral surgery with specialized equipment presents unique surgical considerations.

