Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Menopause01:28

Menopause

175
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
175
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

408
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
408
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

538
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
538
The Menstrual Cycle01:19

The Menstrual Cycle

860
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
860
Stress Prevention and Stress Management Techniques III01:25

Stress Prevention and Stress Management Techniques III

66
Regular exercise and meditation serve as essential tools in managing stress and promoting physical and mental well-being.
The Role of Exercise in Stress Management
Regular physical activity is essential for reducing stress and promoting cardiovascular health. Exercise strengthens the heart, enhances blood flow, keeps blood vessels flexible, and helps lower blood pressure, all of which reduce the body's stress response. Research shows that adults who exercise regularly have nearly half the...
66
Stress Prevention and Stress Management Techniques VI01:30

Stress Prevention and Stress Management Techniques VI

35
Adopting a healthier lifestyle often requires overcoming significant challenges, but leveraging psychological, social, and cultural resources can facilitate meaningful change. Effective self-change hinges on understanding and applying key tools such as motivation and goal setting, which help sustain efforts toward long-term health benefits.
Motivation and Self-Determination
Motivation, the driving force behind behavior, plays a pivotal role at every stage of the change process. The research...
35

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Symptom profiles in the late reproductive stage, earlier premenopause and early perimenopause in the absence of vasomotor symptoms: a cross-sectional study.

BMJ sexual & reproductive health·2026
Same author

Food and Drug Administration, Menopause Hormone Therapies, and Black Box Warnings on Cardiovascular Disease: New Evidence or New Directions?

Circulation. Population health and outcomes·2026
Same author

Transdermal testosterone gel vs placebo in women with diminished ovarian reserve prior to in vitro fertilization: a randomized, clinical trial.

Nature communications·2026
Same author

Non-metastatic breast cancer patients discontinuing aromatase inhibitor on denosumab: what next?

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same author

The impact of transdermal testosterone treatment on quality of life in women with diminished ovarian reserve: secondary analysis of a randomized controlled trial.

Human reproduction (Oxford, England)·2025
Same author

The association between smoking and diabetic neuropathy: a systematic review and meta-analysis.

Systematic reviews·2025
Same journal

The International Menopause Society celebrates another milestone.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Impact of social determinants of health on perimenopause symptom burden: insights from the Flo app.

Climacteric : the journal of the International Menopause Society·2026
Same journal

From tissue to outcome - how perioperative vaginal estrogen transforms prolapse surgery results: a systematic review and meta-analysis of clinical evidence and outcomes.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Mapping menopause education for healthcare professionals: a scoping review.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Portuguese osteopaths' perceptions on the management of musculoskeletal conditions in menopausal women.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Perimenopausal migraine: a narrative review.

Climacteric : the journal of the International Menopause Society·2026
See all related articles

Related Experiment Video

Updated: Jul 12, 2025

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
07:20

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

556

The 2023 Practitioner's Toolkit for Managing Menopause.

S R Davis1,2, S Taylor1, C Hemachandra1,3

  • 1Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

Climacteric : the Journal of the International Menopause Society
|October 30, 2023
PubMed
Summary
This summary is machine-generated.

The updated Practitioner's Toolkit for Managing the Menopause offers current best practices for healthcare providers. It includes revised algorithms for assessing menopausal status and guiding treatment decisions for women at midlife.

Keywords:
Menopausehormone replacement therapyhot flashesmenopausal hormone therapy

More Related Videos

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

12.2K
A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
14:26

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

15.5K

Related Experiment Videos

Last Updated: Jul 12, 2025

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
07:20

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

556
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

12.2K
A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
14:26

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

15.5K

Area of Science:

  • Women's Health
  • Endocrinology
  • Clinical Practice Guidelines

Background:

  • The 2014 Practitioner's Toolkit for Managing the Menopause served as a desk-top resource for healthcare providers assisting women at midlife.
  • A revision was necessary to ensure the Toolkit's algorithms and information align with current best practices in menopause management.

Purpose of the Study:

  • To update the Practitioner's Toolkit for Managing the Menopause with current evidence-based information.
  • To enhance clinical decision-making tools for healthcare providers caring for women experiencing menopause.

Main Methods:

  • A systematic literature search was conducted for guidelines and statements on menopause published after 2014.
  • Key recommendations from robust Clinical Practice Guidelines were extracted.
  • The peer-reviewed literature was searched to address identified information gaps.

Main Results:

  • The revised Toolkit features algorithms for clinical assessment and care of women relevant to menopause.
  • It guides determination of menopausal status, menopause hormone therapy (MHT), and non-hormonal treatments.
  • The Toolkit now includes expanded support for shared decision-making regarding bone health, addressing a previous lack of clear guidelines for asymptomatic women.

Conclusions:

  • The 2023 Toolkit provides updated, accessible information for healthcare providers managing women at midlife.
  • The revised Toolkit has received endorsements from major international and national menopause and endocrine societies.