Woven Endo Bridge shape modification contributes to decrease in adequate occlusion rate after Woven Endo Bridge...

Area of Science:

• Neurosurgery
• Interventional Neuroradiology
• Medical Devices

Background:

• Wide-neck bifurcation intracranial aneurysms (WNBAs) pose treatment challenges.
• The Woven Endo Bridge (WEB) device offers a novel endovascular solution for WNBAs.
• Assessing factors influencing WEB device efficacy is crucial for optimizing patient outcomes.

Purpose of the Study:

• To identify radiological factors associated with adequate occlusion (AO) after WEB device implantation for WNBAs.
• To evaluate the safety and efficacy of the WEB device in treating WNBAs.
• To determine predictors of successful aneurysm occlusion using detailed imaging analysis.

Main Methods:

• Retrospective analysis of 29 patients with WNBAs treated with WEB device implantation.
• Comparison of radiological parameters between patients achieving AO and those with non-AO.
• Multivariate analysis to identify significant contributing factors to AO.

Main Results:

• Adequate occlusion (AO) was achieved in 75.9% of patients at 6-month follow-up.
• Complications were infrequent (6.9%) and did not significantly alter functional status (mRS).
• WEB shape modification (WSM) was the only statistically significant factor associated with non-AO (OR: 0.912, p=0.0287).

Conclusions:

• WEB device implantation is an effective and safe treatment for WNBAs.
• WEB shape modification is a critical factor influencing treatment success.
• Further research is needed to understand and mitigate WSM for improved AO rates.