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Related Concept Videos

Information Processing Approach01:30

Information Processing Approach

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The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
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Autism Spectrum Disorder01:19

Autism Spectrum Disorder

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Revisionist Views of Adolescent and Adult Cognition01:24

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A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
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Learning Disabilities01:25

Learning Disabilities

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Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
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Nephrotic Syndrome II : Assessment and Medical Management01:26

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IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
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Related Experiment Video

Updated: Jul 12, 2025

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Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions.

Ryan Kammeyer1, Ekemini A Ogbu2,3, Jennifer C Cooper4

  • 1Departments of Pediatrics and Neurology, Sections of Child Neurology and Neuroimmunology, University of Colorado School of Medicine, Aurora, CO, USA.

Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence
|October 30, 2023
PubMed
Summary

Cognitive dysfunction in pediatric systemic lupus erythematosus (SLE) is understudied, impacting quality of life. More research is needed on its prevalence, risk factors, and effective management strategies for children with SLE.

Keywords:
Cognitive dysfunctionautoimmune diseasecognitive impairmentneuropsychiatric lupuspediatric systemic lupus erythematosus

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Area of Science:

  • Pediatric Neurology
  • Rheumatology
  • Neuroimmunology

Background:

  • Cognitive dysfunction (CD) is a neurologic complication of pediatric systemic lupus erythematosus (SLE).
  • CD in pediatric SLE is poorly understood and understudied.
  • CD can negatively affect long-term socioeconomic status and quality of life.

Purpose of the Study:

  • To review current knowledge on CD in pediatric SLE.
  • To focus on the application of this knowledge to clinical practice.
  • To identify gaps in understanding and suggest future research directions.

Main Methods:

  • Literature review of existing studies on CD in pediatric SLE.
  • Discussion of diagnostic challenges and clinical screening methods.
  • Analysis of potential impacts and interventions for CD.

Main Results:

  • Data on prevalence, risk factors, and optimal management of CD in pediatric SLE are lacking.
  • Current knowledge is insufficient for effective clinical application.
  • Significant gaps exist in understanding the long-term outcomes of CD.

Conclusions:

  • There is a critical need for further research into cognitive dysfunction in pediatric SLE.
  • Improved understanding is essential for developing effective screening, treatment, and management strategies.
  • Addressing CD is crucial for improving the long-term well-being of children with SLE.