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Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection
Published on: May 24, 2020
Mpox
Kaileen Jafari1, George A Woodward2
1From the Assistant Professor.
Human mpox (formerly monkeypox) is a rare but emerging zoonotic disease. Pediatric mpox cases are uncommon, but healthcare providers should recognize its features for prompt diagnosis and care.
Area of Science:
- Infectious Diseases
- Public Health
- Pediatrics
Background:
- Human mpox is a zoonotic viral disease causing smallpox-like illness.
- First identified in 1970, mpox outbreaks were historically localized to endemic regions.
- A 2022 global surge led to a Public Health Emergency of International Concern declaration.
Purpose of the Study:
- To inform pediatric emergency and urgent care providers about mpox in children and adolescents.
- To highlight the clinical features, treatment, and prophylaxis of mpox in pediatric populations.
- To raise awareness of mpox as an emerging infectious disease affecting young individuals.
Main Methods:
- Review of mpox epidemiology and clinical data, focusing on pediatric cases.
- Analysis of case distribution in nonendemic countries, particularly the US.
- Synthesis of information on transmission, clinical presentation, and management strategies.
Main Results:
- Mpox cases in US children and adolescents represented only 0.3% of total cases as of September 2022.
- Most pediatric infections resulted from direct household contact with an infected individual.
- The majority of mpox cases globally and in the US occurred in adults, particularly men who have sex with men.
Conclusions:
- While uncommon, mpox poses a risk to children and adolescents.
- Pediatric healthcare providers need to be prepared for potential mpox cases.
- Awareness of mpox clinical features, treatment, and prophylaxis is crucial for effective pediatric care.
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