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Updated: Jul 12, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
12-Month Efficacy of Advanced Hybrid Closed-Loop System in Adult Type 1 Diabetes Patients
Laura Nigi1,2, Gabriele Iraci Sareri1, Dorica Cataldo2
1Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Abstract:
Automated insulin delivery (AID) systems have improved glycemic control in individuals with type 1 diabetes (T1D). The "advanced hybrid closed loop" (AHCL) stands out as the most recent development in AID systems for T1D management. In a real-world clinical environment, we retrospectively evaluated the AHCL MiniMed™ 780G system's effectiveness to achieve and sustain glycemic control over a 12-month period in 22 adult T1D subjects. Within just 14 days of activating the automatic mode, the AHCL MiniMed 780G system showed rapid improvement in glycemic control, which persisted for 12 months. These findings underscore the effectiveness of AHCL systems in achieving and preserving optimal glycemic control in adults with T1D over a very long follow-up.
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