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Network meta-analysis of comparative efficacy and safety of intubation devices in children

Yu Ming1, Shujuan Chu2, Kai Yang2

  • 1College of Medicine and Health Science, Wuhan Polytechnic University, Wuhan, 430023, Hubei, China.

Scientific Reports
|October 31, 2023
PubMed

Insights

In pediatric intubation, Airtraq devices offer the highest first-pass success rate (FPS). Canada devices excel in reducing time to intubation (TTI), while KingVision devices minimize local complications (LC).

Area of Science:

  • Pediatric critical care medicine
  • Anesthesiology and airway management
  • Medical device comparative effectiveness

Background:

  • Pediatric intubation requires effective and safe devices.
  • Comparative data on various intubation devices in children is limited.
  • Optimizing first-pass success, intubation time, and complication rates is crucial.

Purpose of the Study:

  • To compare the efficacy and safety of different intubation devices in pediatric patients.
  • To identify optimal devices for first-pass success (FPS), time to intubation (TTI), and local complications (LC).

Main Methods:

  • A network meta-analysis of 23 randomized comparative trials (RCTs) involving 12 intubation devices.
  • Data sourced from PubMed, EMBASE, and Cochrane Library literature searches.
  • Primary outcome: first-pass success (FPS); Secondary outcomes: time to intubation (TTI) and local complications (LC).

Main Results:

  • Airtraq, Miller, Glidescope, and McGrath devices showed higher FPS than Macintosh.
  • Airtraq demonstrated superior FPS compared to Glidescope.
  • Canada devices were superior for TTI, and Airtraq reduced LC risk versus Macintosh and Pentax.

Conclusions:

  • Airtraq may be the optimal device for achieving first-pass success in pediatric intubation.
  • Canada devices appear most effective for minimizing time to intubation.
  • KingVision devices may offer the lowest risk of local complications.

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