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ForceGen: End-to-end de novo protein generation based on nonlinear mechanical unfolding responses using a protein

Bo Ni1, David L Kaplan2, Markus J Buehler1,3,4

  • 1Laboratory for Atomistic and Molecular Mechanics (LAMM), Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.

Arxiv
|October 31, 2023
PubMed
Abstract

Keywords:
Generative deep learningLanguage diffusion modelProtein designde novo proteinsmechanical unfoldingstrength and toughness

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