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Factors associated with COVID-19 vaccination coverage in hypertensive patients with Omicron infection in Shanghai,

Kongbo Zhu1, Shaolei Ma2, Hui Chen3

  • 1Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.

Human Vaccines & Immunotherapeutics
|October 31, 2023
PubMed

Insights

COVID-19 vaccine uptake, particularly booster doses, was low among hypertensive patients during the Omicron wave. Older age, female sex, and comorbidities were linked to lower vaccination rates, necessitating targeted interventions for this high-risk group.

Area of Science:

  • Epidemiology
  • Public Health
  • Immunology

Background:

  • The diminishing protective immunity from prior infection and mixed immunity highlights the importance of vaccination for sustained COVID-19 protection.
  • Hypertensive individuals represent a vulnerable population susceptible to severe COVID-19 outcomes.
  • Understanding vaccination patterns in this group is crucial for future public health strategies.

Purpose of the Study:

  • To assess the vaccination status of hypertensive patients infected with the Omicron variant of COVID-19.
  • To identify characteristics and risk factors associated with non-vaccination in this cohort.
  • To inform targeted interventions for improving vaccine coverage in hypertensive populations.

Main Methods:

  • A cohort of 4576 hypertensive patients with Omicron infection was analyzed.
  • Data on vaccination status (at least one dose, booster dose) were collected.
  • Multivariate logistic regression identified factors associated with vaccination status.

Main Results:

  • 77.7% received at least one vaccine dose, and 45.0% received a booster dose.
  • Male sex, younger age, and absence of comorbidities were associated with higher vaccination rates.
  • Female sex, increasing age, and presence of diabetes, chronic pulmonary, kidney, or other cancers were associated with lower vaccination rates.

Conclusions:

  • Vaccine coverage, especially for boosters, was suboptimal in hypertensive patients with Omicron infection.
  • Factors such as female sex, advanced age, and comorbidities are linked to under-vaccination.
  • Tailored public health initiatives are essential to enhance COVID-19 vaccination rates among diverse hypertensive patient groups.

Keywords:
COVID-19SARS-CoV-2hypertensionomicronvaccine

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