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Updated: Jul 12, 2025

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
Published on: August 20, 2021
Complete genome assembly of Enterococcus faecalis strain HL1, isolated from an infant fecal sample
Kyoung Su Kim1, Gun-Hyeong Lee1, Hyun Ryul Bak1
1Department of Biotechnology, Yonsei University , Seoul, South Korea.
Insights
We sequenced the genome of Enterococcus faecalis HL1 from infant feces. This bacterium shows therapeutic potential, with its genome containing 2,546 coding genes and no plasmids.
Area of Science:
- Microbiology
- Genomics
- Bioinformatics
Background:
- Enterococcus faecalis is a significant bacterium with notable therapeutic potential.
- Understanding the genomic makeup of E. faecalis strains is crucial for harnessing its applications.
Purpose of the Study:
- To present the complete genome sequence of Enterococcus faecalis strain HL1.
- To analyze the genomic features of this strain isolated from infant feces.
Main Methods:
- Whole-genome sequencing of Enterococcus faecalis strain HL1.
- Bioinformatic analysis to identify coding genes and genomic structure.
Main Results:
- The complete genome sequence of E. faecalis HL1 was determined.
- The genome comprises a 2.7 Mb circular chromosome without plasmids.
- A total of 2,546 predicted coding genes were identified.
Conclusions:
- The genome sequence provides a foundation for further research into the therapeutic applications of E. faecalis HL1.
- The genomic characteristics of strain HL1 offer insights into its biological functions and potential uses.
Abstract:
We present the complete genome sequence of Enterococcus faecalis strain HL1, isolated from infant feces. E. faecalis gains significant attention for its therapeutic potential. The genome of E. faecalis HL1 consists of a 2.7 Mb circular chromosome with no plasmids, and it contains a total of 2,546 predicted coding genes.
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