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Updated: Jul 12, 2025

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Long Range Electronic Effects on the Host-Guest Complexation within the Oxygen Depleted 5,5'-Bicalixarene Cavities
Michal Farber1, Pintu Maity1, Abhishek Baheti1
1School of Chemistry, The Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Abstract:
We report the synthesis of a series of the oxygen-depleted conjugated 5,5'-Bicalix[4]arene compounds bearing various substituents at the terminal positions of the conjugated chain and their fluorescence response to the presence of a cationic N-methylpyridinium guest. The complexation of this cation within the bicalixarene cavity results in the fluorescence quenching, with the host molecules bearing electron-donating groups demonstrating a stronger fluorescence response. These results show the importance of the electronic effects on the host-guest complexation within the hydrophobic calixarene scaffolds.
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