Plethysmograph Variability Index Values in Healthy Neonates - An Observational Pilot Study

Area of Science:

• Neonatal physiology
• Non-invasive monitoring

Background:

• Fluid responsiveness assessment is critical in neonates.
• Plethysmograph variability index (PVI) is a non-invasive tool for fluid responsiveness.
• Establishing normative data for PVI in neonates is essential.

Purpose of the Study:

• To establish normative data for PVI in healthy term and late preterm neonates.
• To provide a reference range for PVI in the neonatal population.

Main Methods:

• Healthy term and late preterm neonates were enrolled.
• PVI was measured using pulse oximetry during the first three days of life.
• Data analysis was performed using SPSS software.

Main Results:

• The median PVI in neonates was 21, with a wide range.
• PVI distribution was consistent across different days of life, gestational ages, genders, and weights.
• No significant correlation was found between PVI and heart rate, gestational age, or birth weight.

Conclusions:

• Normative PVI data for neonates has been established.
• Serial monitoring of PVI trends is more valuable for clinical decision-making than isolated values.
• PVI can be a useful tool for fluid management in neonates.