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Updated: Jul 12, 2025

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis
Published on: August 17, 2022
[Asociation between fluid overload and mortality in pediatric patients in the intensive care unit]
Alexi Chávez-Valdivia1, Paola Rojas-Vivanco1, Alejandra Castañeda1
1Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Insights
Fluid overload (FO) significantly increases mortality risk in pediatric intensive care unit (PICU) patients. This study confirms FO as an independent risk factor, highlighting its critical impact on survival outcomes.
Area of Science:
- Pediatric critical care medicine
- Clinical epidemiology
- Fluid management in intensive care
Objective:
To assess the association between fluid overload (FO) and other risk fac tors in the mortality of patients admitted to the Pediatric Intensive Care Unit (PICU).
Patients And Method:
A historical cohort study was conducted. Pediatric patients older than one month and younger than 18 years who were hospitalized in the PICU for more than 48 hours during 2016 were included. Demographic and clinical data were recorded. FO was calculated as [Sum of daily (fluid in - fluid out)/weight at ICU admission] x 100. Poisson regression analysis was perfor med to determine factors associated with mortality.
Results:
171 patients were included. The median age was 31 months (RIQ 8; 84). Mortality was 8.18%. FO in the surviving population was 7% and 11.5% in the deceased patients (p < 0.05). The adjusted analysis identified FO as a major risk factor for mortality with a Relative Risk 1.32 (1.24 - 1.40); age and Glasgow Coma Scale were protective factors.
Conclusion:
Fluid overload is an independent risk factor for mortality in the analyzed PICU cohort.
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