Related Experiment Video
Updated: Jul 12, 2025

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
Published on: February 15, 2018
[Exclusive breastfeeding and disease evolution in hospitalized infants with bronchiolitis]
Felicitas Giunchetti1, Leila E Hidalgo1, Marisol Penas1
1Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina.
Insights
Exclusive breastfeeding (EBF) significantly reduces hospitalization duration and oxygen therapy needs in infants with bronchiolitis compared to breast milk substitutes (BMS). This highlights the benefits of EBF for hospitalized infants.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neonatal Care
Context:
- Bronchiolitis is a leading cause of infant hospitalization.
- Breastfeeding is known to prevent infections, but its impact on hospitalized bronchiolitis patients is less understood.
Purpose:
- To compare the clinical outcomes of infants hospitalized with bronchiolitis based on their feeding method: exclusive breastfeeding (EBF) versus breast milk substitutes (BMS).
Summary:
- A prospective cohort study of 131 infants (1-6 months) hospitalized for bronchiolitis compared outcomes for EBF, BMS, and mixed feeding groups.
- The EBF group showed significantly shorter hospital stays and reduced need for oxygen therapy compared to the BMS group.
- No significant differences were observed in high-flow nasal cannula use, pneumonia, intensive care transfers, or mortality.
Impact:
- Exclusive breastfeeding is associated with improved recovery and shorter hospital stays for infants hospitalized with bronchiolitis.
- Findings support the continued recommendation of exclusive breastfeeding for infants, even those requiring hospitalization.
- This research provides evidence for optimizing care and resource allocation in pediatric respiratory infections.
Abstract:
Bronchiolitis is the main reason for hospitalization in infancy. Breastfeeding is a protective factor aga inst infections, however, although there is evidence that breastfeeding could prevent hospitalizations due to bronchiolitis, its effect in patients already hospitalized because of this disease is less clear.
Objective:
To evaluate if there are differences in the evolution of patients hospitalized due to bronchiolitis fed with exclusive breastfeeding (EBF) vs. breast milk substitutes (BMS).
Patients And Method:
Prospec tive cohort study. Children hospitalized due to bronchiolitis aged from 1 to 6 months were included. Evolution was compared with respect to days of hospitalization, days of oxygen therapy, requirement of high-flow nasal cannula (HFNC), presence of associated pneumonia, transfer to intensive care, and death.
Results:
During the study period, 131 infants hospitalized due to bronchiolitis met the selection criteria, 54 were fed with EBF, 29 with BMS, and 48 received mixed feeding. The EBF group required significantly fewer days of oxygen therapy (5.1 ± 2.4 vs. 6.6 ± 3.5; p < 0.02) and hospitalization (7.0 ± 2.4 vs. 8.4 ± 3.6; p < 0.04) than the BMS group. Although males in the BMS group required on average more days of hospitalization and oxygen therapy, this difference was not statistically significant. No deaths were recorded in the groups studied.
Conclusion:
Patients fed with EBF required fewer days of oxygen therapy and hospitalization than those who received BMS.
More Related Videos
08:12Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
05:31Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Related Concept Videos
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Pneumonia II: Pathophysiology
Pulmonary Cycle: Exhalation
Pneumonia III: Complications and Assessment
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...