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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
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Distinctive Features of Adult Stem Cells vs Cancer Stem Cells01:18

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A stem cell is an unspecialized cell that can divide without limit as needed and can, under specific conditions, differentiate into specialized cells.
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Adult stem cells are tissue-specific; hence, they divide to develop the tissue from which they originate. One type of adult stem cell is the epithelial stem cell, which gives rise to the keratinocytes in the multiple layers of epithelial cells in the epidermis of the skin. Adult bone marrow has three distinct types of stem cells:...
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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Embryonic Stem Cells00:58

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
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What counts as STEM, and does it matter?

Rebecca M Adler1, Mingkai Xu1, Bethany Rittle-Johnson1

  • 1Department of Psychology and Human Development, Vanderbilt University, Nashville, Tennessee, USA.

The British Journal of Educational Psychology
|October 31, 2023
PubMed
Summary
This summary is machine-generated.

Students

Keywords:
STEM career interestgendermath motivationscience motivation

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Area of Science:

  • STEM Education
  • Career Development
  • Psychology

Background:

  • Accurate measurement of Science, Technology, Engineering, and Mathematics (STEM) career interest requires understanding students' perceptions of STEM careers.
  • Students' conceptualizations of STEM careers are complex and not always aligned with traditional definitions.

Purpose of the Study:

  • To investigate whether students include medical careers within their definition of STEM.
  • To examine if factors predicting STEM career interest differ based on whether medical careers are included in the STEM definition.

Main Methods:

  • Study 1: Online questionnaire with 125 US college students.
  • Study 2: Survey with 455 US 10th-grade students assessing math achievement, motivation, and career interest.

Main Results:

  • Medical careers were viewed as STEM more often than non-STEM but less than traditional STEM careers.
  • Science importance value predicted interest in STEM+Medicine careers, but not traditional STEM.
  • Gender differences emerged: boys favored traditional STEM, girls favored STEM+Medicine.

Conclusions:

  • Students' understanding of STEM is nuanced and not strictly binary.
  • Researchers should clearly define STEM in studies, coding, and publications to ensure clarity and comparability.