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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Drug-Induced Erythema Multiforme.

Peeyush Shivhare1, Naqoosh Haidry1, Anka Sharma2

  • 1Department of Dentistry, All India Institutes of Medical Sciences, Patna 801507, India.

Case Reports in Dermatological Medicine
|November 1, 2023
PubMed
Summary

Erythema multiforme (EM) is a skin condition often triggered by herpes infections or drug reactions. This case series reviews four instances of drug-induced EM and their treatments.

Area of Science:

  • Dermatology
  • Immunology
  • Pharmacology

Background:

  • Erythema multiforme (EM) is an acute inflammatory mucocutaneous condition with characteristic target lesions.

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  • EM presents in minor to major forms, often with acral distribution.
  • Etiology is multifactorial, with herpes simplex virus (HSV) infections in 90% and drug intake in 10% of cases.