Advanced age - a critical risk factor for recurrent miscarriage

Recurrent spontaneous abortion (RSA) is a multifactorial disease that seriously affects womens physical and mental health. With the advent of efficient contraception, the trend for women towards later maternity until their thirties or even forties. Nevertheless, the risk of miscarriage is strongly related to maternal age. We performed a retrospective analysis to evaluate the etiology of RSA through age groups. The results demonstrated that intrauterine adhesions and ovarian dysfunction were responsible for increased miscarriages in older RSA patients. In conclusion, older women will bear a higher risk of miscarriage, mainly due to uterine adhesions or decreased ovarian function.