Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

125
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
125
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

97
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
97
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

21
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
21
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

18
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
18
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

12
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
12
Positron Emission Tomography01:29

Positron Emission Tomography

4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-perspective region-based CNNs for vertebrae labeling in intraoperative long-length images.

Computer methods and programs in biomedicine·2022
Same author

IS REPEAT FNAB NECESSARY FOR THYROID NODULES WITH ND / UNS CYTOLOGY?

Acta endocrinologica (Bucharest, Romania : 2005)·2022
Same author

The effect of strap muscle transection on voice and swallowing changes after thyroidectomy in patients without laryngeal nerve injury.

Annals of the Royal College of Surgeons of England·2021
Same author

Facial Emotion Recognition Ability in Patients with Fibromyalgia.

La Clinica terapeutica·2021
Same author

3D vertebrae labeling in spine CT: an accurate, memory-efficient (Ortho2D) framework.

Physics in medicine and biology·2021
Same author

MRI features of intra-axial histiocytic brain mass lesions.

Clinical radiology·2020

Related Experiment Video

Updated: Jul 12, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

3.5K

INTERRELATION BETWEEN PREOPERATIVE TESTS, INTRAOPERATIVE FINDINGS AND OUTCOMES OF 99M-TECHNETIUM-SESTAMIBI SCAN IN

M Kostek1, N Aygun1, M T Unlu1

  • 1University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Department of General Surgery, Sisli, Istanbul, Turkey.

Acta Endocrinologica (Bucharest, Romania : 2005)
|November 1, 2023
PubMed
Summary

Preoperative parathyroid hormone (PTH) levels and adenoma size are key indicators for predicting the accuracy of Technetium-99m-methoxyisobutylisonitrile (MIBI) scans in primary hyperparathyroidism surgery.

Keywords:
99m-Technetium-Sestamibi scanPrimary hyperparathyroidismparathyroid hormone

More Related Videos

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

1.9K
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

3.7K

Related Experiment Videos

Last Updated: Jul 12, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

3.5K
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

1.9K
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

3.7K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Nuclear Medicine

Background:

  • Primary hyperparathyroidism (PHPT) is a common endocrine disorder.
  • Surgery is the primary treatment, with minimally invasive approaches gaining prominence.
  • Accurate preoperative localization is crucial for successful parathyroid surgery.

Purpose of the Study:

  • To investigate the correlation between preoperative biochemical markers, intraoperative findings, and Technetium-99m-methoxyisobutylisonitrile (MIBI) scan results in PHPT patients.
  • To identify predictors of MIBI scan accuracy.

Main Methods:

  • Retrospective clinical study of 185 PHPT patients operated between January 2010 and October 2018.
  • Patients were grouped based on MIBI scan results (positive vs. negative).
  • Analysis of preoperative serum calcium, parathyroid hormone (PTH), creatinine, magnesium, phosphorus, alkaline phosphatase, 25-OH Vitamin D3, and adenoma characteristics (diameter, volume).

Main Results:

  • Significant differences in mean preoperative PTH levels (p<0.02) and adenoma size (diameter p<0.0001, volume p<0.0001) between MIBI-positive and MIBI-negative groups.
  • No statistical differences in other tested biochemical parameters.
  • Optimal cut-off values identified: adenoma diameter 1.55 cm, volume 0.48 cm³, and preoperative PTH 124.5 ng/L for MIBI scan positivity.

Conclusions:

  • Preoperative serum PTH levels and adenoma dimensions are valuable in predicting MIBI scan accuracy.
  • These factors may help anticipate the need for additional localization studies prior to surgery.