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Public health impact and return on investment of the pediatric immunization program in Poland
Claire E Mellott1, Rafal Jaworski2, Justin Carrico1
1RTI Health Solutions, Research Triangle Park, NC, USA.
Insights
The Polish pediatric immunization program (PIP) significantly reduced disease cases and deaths, offering substantial economic benefits. Continued investment in childhood vaccination is crucial for public health and cost savings.
Area of Science:
- Public Health
- Health Economics
- Epidemiology
Background:
- The pediatric immunization program (PIP) in Poland lacked systematic evaluation.
- Childhood vaccination is a cornerstone of public health initiatives.
Purpose of the Study:
- To assess the epidemiological impact of Poland's PIP.
- To determine the return on investment of the PIP from healthcare and societal viewpoints.
Main Methods:
- A health-economic model was developed for 9 vaccines targeting 11 pathogens in children aged 0-6 years.
- The 2019 birth cohort was followed over their lifetime, comparing outcomes with and without the PIP.
Main Results:
- The PIP prevented over 452,300 disease cases and 1,600 deaths.
- The program yielded a benefit-cost ratio of 2.2 (healthcare) and 7.6 (societal).
- Significant savings were observed: €65 million (healthcare) and €358 million (societal).
Conclusions:
- The Polish PIP demonstrates substantial disease prevention and cost reduction.
- The study underscores the value of sustained investment in pediatric immunization programs in Poland.
Background:
This study aims to evaluate the epidemiological impact and return on investment of the pediatric immunization program (PIP) in Poland from the healthcare-sector and societal perspectives.
Research Design And Methods:
A health-economic model was developed focusing on the nine vaccines, targeting 11 pathogens, recommended by the public health authorities for children aged 0-6 years in Poland. The 2019 birth cohort (388,178) was followed over their lifetime, with the model estimating discounted health outcomes, life-years gained, quality-adjusted life-years, and direct and indirect costs with and without the PIP based on current and pre-vaccine - era disease incidence estimates, respectively.
Results:
Across 11 targeted pathogens, the Polish PIP prevented more than 452,300 cases of disease, 1,600 deaths, 37,900 life-years lost, and 38,800 quality-adjusted life-years lost. The PIP was associated with vaccination costs of €54 million. Pediatric immunization averted €65 million from a healthcare-sector perspective (benefit-cost ratio [BCR], 2.2) and averted €358 million from a societal perspective (BCR, 7.6). The BCRs from both perspectives remained >1.0 in scenario analyses.
Conclusions:
The Polish PIP, which has not previously been systematically assessed, brings large-scale prevention of disease-related morbidity, premature mortality, and associated costs. This analysis highlights the value of continued investment in pediatric immunization in Poland.
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