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Updated: Jul 12, 2025

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Twin Gestation With Spontaneous Reduction To Singleton

Kristina E Sondgeroth1

  • 1SIU School of Medicine, Springfield, Illinois.

Clinical Obstetrics and Gynecology
|November 1, 2023
PubMed

Twin gestations are at increased risk of single intrauterine fetal death. A first-trimester loss is a common complication in twin gestations. The rate of co-twin morbidity and mortality is higher when a single demise occurs in the second and third trimesters. Monochorionicity strongly influences the prognosis for the surviving co-twin. Fetal ultrasound combined with MRI may be able to help predict neurological injury to the surviving co-twin. The rate of co-twin demise decreases with advancing gestation. After single intrauterine fetal demise, monochorionic gestations should be delivered by 34 weeks and dichorionic by 36 to 37 weeks gestation.

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