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Optimal Changes Seen in Patients After Treatment With Poly- l -Lactic Acid: A Retrospective Descriptive Study.

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Summary

Poly-L-lactic acid (PLLA) injections effectively restore facial volume and improve skin texture. Key visible changes include enhanced facial contouring, a lifting effect, and reduced nasolabial folds, confirming PLLA

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Area of Science:

  • Aesthetic Medicine
  • Dermatology
  • Cosmetic Surgery

Background:

  • Poly-L-lactic acid (PLLA) is a collagen biostimulator popular for facial volume restoration and wrinkle improvement.
  • Its long-lasting effects are recognized, but specific visible facial changes require detailed characterization.

Purpose of the Study:

  • To identify and characterize the visible changes following facial Poly-L-lactic acid (PLLA) injections.
  • To provide a comprehensive understanding of PLLA's aesthetic outcomes.

Main Methods:

  • Retrieved data from 678 patients who received 2-3 PLLA treatments (2021-2022).
  • 31 international evaluators assessed before-and-after images of 12 patients with significant improvement.
  • Evaluations focused on changes observed approximately 7 months post-final injection.

Main Results:

  • 1,015 descriptions categorized into key aesthetic improvements.
  • Primary changes included enhanced lateral facial contouring and lifting effect.
  • Secondary outcomes involved nasolabial fold improvement, increased skin firmness, and better skin texture.

Conclusions:

  • PLLA injections demonstrate efficacy in facial contouring, lifting, and skin texture enhancement.
  • Further research is recommended to validate findings and develop a PLLA assessment scale.