Functional micro-/nanostructured gallium-based liquid metal for biochemical sensing and imaging applications
1Department of Chemistry, Beijing Key Laboratory for Analytical Methods and Instrumentation, Kay Lab of Bioorganic Phosphorus Chemistry and Chemical Biology of Ministry of Education, Tsinghua University, Beijing, 100084, China.
Biosensors & Bioelectronics
|November 1, 2023
Summary
Gallium-based liquid metals (LMs) offer advanced capabilities for biochemical sensing and imaging. This review highlights their micro-/nanostructured forms and applications in various analytical techniques.
Area of Science:
- Materials Science
- Nanotechnology
- Analytical Chemistry
Background:
- Liquid metals (LMs), particularly gallium (Ga)-based ones, are increasingly recognized for their diverse research applications.
- Ga-based LMs possess unique properties like high conductivity, large surface area, biocompatibility, small bandgap, and elasticity, making them suitable for advanced sensors.
- Recent progress focuses on functional micro-/nanostructured Ga-based LMs for enhanced biochemical sensing and imaging.
Purpose of the Study:
- To comprehensively review the latest advancements in functional micro-/nanostructured Ga-based LMs.
- To summarize their applications in biochemical sensing and biomedical imaging.
- To provide insights into future research directions and challenges.
Main Methods:
- Discussion of electrical, optical, and biocompatible features of Ga-based LM micro-/nanoparticles.
- Overview of manufacturing and functionalization processes for these materials.
- Demonstration of Ga-based LMs in various sensing and imaging techniques.
Main Results:
- Ga-based LMs show significant potential in electrochemical, electrochemiluminescence, and optical sensing.
- Their application in biomedical imaging is rapidly advancing.
- Functional micro-/nanostructuring enhances their performance in these areas.
Conclusions:
- Ga-based LMs are highly promising for next-generation biochemical sensing and imaging platforms.
- Further research is needed to overcome existing challenges and fully realize their potential.
- Continued development in micro-/nanostructuring and functionalization will drive innovation.


