Related Experiment Video

Updated: Jul 12, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:15

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

74

Weight fluctuations preceding and succeeding heart failure diagnosis: Implications for all-cause mortality

Haibo Gao1, Wei Li2, Yifei Wang2

  • 1Department of Cardiology, Tangshan Gongren Hospital, Tangshan, Hebei, 063000, China; Graduate School, Hebei Medical University, Shijiazhuang, Hebei, 050011, China.

Current Problems in Cardiology
|November 1, 2023
PubMed

Insights

Weight loss before and after heart failure (HF) diagnosis significantly increases mortality risk. This finding highlights the importance of monitoring weight changes in HF patients for better outcomes.

Area of Science:

  • Cardiology
  • Clinical Research
  • Public Health

Background:

  • Heart failure (HF) is a major global health concern.
  • Understanding prognostic factors in HF is crucial for patient management.
  • Weight changes can influence HF outcomes.

Purpose of the Study:

  • To investigate the impact of weight fluctuations before and after heart failure diagnosis on all-cause mortality.
  • To identify weight changes as a potential independent risk factor for mortality in HF patients.

Main Methods:

  • A cohort of individuals diagnosed with HF between 2006 and 2018 from the Kailuan Group health assessments was analyzed.
  • Mortality data was collected until December 31, 2021.
  • COX proportional hazards regression models were used to assess mortality risk, adjusting for confounders.

Main Results:

  • Over a mean follow-up of 5.8 years, 30.7% of 3115 participants died.
  • Weight reduction (Q1 category) was associated with significantly higher hazard ratios for mortality (1.71 [1.43-2.05]) compared to the Q3 category, after adjusting for confounders.

Conclusions:

  • Pre- and post-diagnosis weight reduction is an independent risk factor for all-cause mortality in heart failure patients.
  • These findings underscore the prognostic significance of weight loss in heart failure.
  • Clinical monitoring of weight changes in HF patients is recommended.
Abstract

Keywords:
Heart failureMortalityWeight changeWeight loss

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