Related Experiment Video
Updated: Jul 12, 2025

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
Sjögren Syndrome: A Forgotten or an Overdiagnosed Entity?
1X. Mariette, MD, PhD, Rheumatology Department, Université Paris-Saclay, Hôpital Bicêtre, AP-HP, INSERM UMR1184, Le Kremlin Bicêtre, Paris, France.
Abstract:
In this issue of The Journal of Rheumatology, Lee et al present an interesting editorial claiming that seronegative Sjögren syndrome (SS) is a forgotten entity.1 They provide convincing arguments supporting this assertion. As reminded by the authors, it is crucial to distinguish patients with seronegative SS from patients living with sicca symptoms, because the former group may experience potentially serious extraglandular manifestations, and thus require entirely different therapeutic approaches than patients with sicca symptoms without any autoimmune disorders.
More Related Videos
Related Concept Videos
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Nephrotic Syndrome I : Introduction
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
Nephrotic Syndrome II : Assessment and Medical Management
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

