Aloe Barbadensis Miller (Aloe Vera)

Area of Science:

• Pharmacology
• Natural Products
• Medicinal Chemistry

Background:

• Aloe Barbadensis Miller (Aloe Vera, AV) is recognized for extensive health, skincare, and medicinal benefits.
• AV contains over 200 bioactive compounds, including phenolic acids, flavonoids, and polysaccharides, primarily in its inner leaf gel.

Purpose of the Study:

• To provide a comprehensive review of AV's bioactive constituents.
• To summarize its pharmacological activities, potential applications, and clinical evidence for disease prevention.
• To discuss toxicological data and adverse effects.

Main Methods:

• This study is a narrative review.
• It synthesizes findings from clinical studies on humans and animals.
• It analyzes data on AV's bioactive compounds and their effects.

Main Results:

• AV demonstrates efficacy in reducing blood glucose, antioxidant and immunomodulatory effects.
• It exhibits anticancer properties by inducing apoptosis, protects the liver, and has antimicrobial effects.
• AV promotes skin and oral health, but potential risks necessitate caution.

Conclusions:

• AV possesses significant therapeutic potential across various health domains.
• Adherence to dosages and expert consultation are crucial for safe use.
• Further randomized controlled trials are essential to validate benefits and assess risks.