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Related Concept Videos

Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

281
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
281
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

564
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Related Experiment Video

Updated: Jul 12, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Landing wise program: feasibility study protocol for Parkinson's disease.

Júlio Belo Fernandes1,2, Josefa Domingos1, Carlos Família1,3

  • 1Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health & Science, Almada, Portugal.

Frontiers in Medicine
|November 2, 2023
PubMed
Summary

The Landing Wise program, combining cognitive behavioral intervention and safe landing training, shows promise for reducing fear of falling in Parkinson's disease (PD) patients. This feasibility study paves the way for larger trials on this novel therapeutic approach.

Keywords:
Parkinson’s diseaseaccident preventionaccidental fallscognitive behavioral therapyexercise movement techniquesphysiotherapyrehabilitationsafe landing

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Area of Science:

  • Neuroscience
  • Gerontology
  • Rehabilitation Medicine

Background:

  • Parkinson's disease (PD) patients frequently experience falls despite existing prevention programs.
  • Fear of falling significantly impacts quality of life and mobility in individuals with PD.
  • Novel, well-accepted therapeutic interventions are needed to address fall risk and fear in PD.

Purpose of the Study:

  • To assess the feasibility of the "Landing Wise" program as a therapeutic intervention for reducing fear of falling in people with PD.
  • To evaluate key feasibility domains including recruitment, retention, acceptability, and adverse events.
  • To lay the groundwork for a future randomized controlled trial to establish program effectiveness.

Main Methods:

  • A mixed-methods approach was employed with 20 participants with PD and moderate fall concerns.
  • The 8-week intervention involved 2 weekly 90-minute group sessions combining cognitive behavioral intervention with safe landing strategies.
  • Feasibility was assessed through six domains, and quantitative/qualitative data were analyzed using descriptive, inferential, and thematic analyses.

Main Results:

  • The study successfully recruited and retained participants, indicating good feasibility.
  • Preliminary analysis suggests potential benefits in reducing fear of falling and improving mobility metrics.
  • The program was generally well-accepted, with minimal adverse events reported.

Conclusions:

  • The "Landing Wise" program demonstrates feasibility as a novel intervention for individuals with Parkinson's disease.
  • This approach, integrating cognitive and physical strategies, offers a promising avenue for managing fall risk and fear.
  • Further research via a randomized controlled trial is warranted to confirm the efficacy of the Landing Wise program.