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Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Related Experiment Video

Updated: Jul 12, 2025

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms
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Transform diabetes care with precision medicine.

Sharumathy Kannan1, Dinesh Kumar Chellappan2, Chia Siang Kow3

  • 1School of Health Sciences International Medical University Kuala Lumpur Malaysia.

Health Science Reports
|November 2, 2023
PubMed
Summary

Precision medicine revolutionizes diabetes care by integrating personal data for tailored treatments. Collaboration is key for implementing these advanced, personalized diabetes strategies effectively.

Keywords:
artificial intelligencebeta cell transplantationdiabetesdiabetes nanomedicineprecision medicine

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Area of Science:

  • Endocrinology
  • Genomics
  • Personalized Medicine

Background:

  • Diabetes mellitus represents a significant global health challenge.
  • Advancements in understanding diabetes pathophysiology are ongoing.

Purpose of the Study:

  • To explore the role and impact of precision medicine in diabetes care.
  • To highlight technological advancements and challenges in personalized diabetes management.

Main Methods:

  • A comprehensive literature search was performed across major scientific databases.
  • Studies focused on precision medicine applications in diabetes management were systematically reviewed.

Main Results:

  • Precision medicine integrates diverse personal data (clinical, genetic, lifestyle, biomarkers) for tailored diabetes treatments.
  • It enables targeted therapies based on individual genetic makeup, molecular profiles, and phenotypic traits.
  • Key technologies enabling personalized diabetes care and associated challenges were identified.

Conclusions:

  • Effective implementation of precision diabetes medicine necessitates multi-stakeholder collaboration and coordination.
  • Interdisciplinary efforts are vital for advancing personalized approaches in diabetes management.