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Risk factors associated with saphenous vein graft aneurysm after coronary artery bypass graft
Bikona Ghosh1, Thiyagarajan SIbi Krishna2, Aishwarya Boini3
1Dhaka Medical College Hospital, Dhaka, Bangladesh.
Insights
Saphenous vein graft aneurysm (SVGA) is a rare complication after coronary artery bypass grafting (CABG). Atherosclerosis with intimal calcification is the most frequent risk factor identified in post-CABG patients.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Medical Complications
Background:
- Saphenous vein graft aneurysm (SVGA) is a rare but serious complication post-coronary artery bypass grafting (CABG).
- Identifying risk factors for SVGA is crucial for patient management and improving outcomes.
Purpose of the Study:
- To identify potential risk factors associated with the development of SVGA in patients who have undergone CABG.
Main Methods:
- A systematic review of multiple databases (PubMed, Web of Science, Scopus, EMBASE, Google Scholar) was conducted.
- Included studies were observational, reviews, meta-analyses, case studies, and case series involving adult patients with SVGA post-CABG.
- Data extraction and assessment were performed by two independent investigators following PRISMA guidelines.
Main Results:
- Out of 487 finalized articles, 14 met the inclusion criteria, reporting 12 cases of SVGA after CABG.
- Atherosclerosis with intimal calcification was the most prevalent risk factor.
- Other identified risk factors included infection, hyperlipidemia, pneumonia, and cardiac pathologies.
Conclusions:
- Atherosclerosis with intimal calcification is the primary risk factor for SVGA following CABG.
- Early detection and regular follow-up imaging are associated with improved patient outcomes.
- Further research is needed to fully elucidate the risk variables in SVGA development.
Introduction:
Saphenous vein graft aneurysm (SVGA) is a rare but life-threatening complication following coronary artery bypass grafting (CABG). The authors aim to identify the potential risk factors that lead to SVGA in post-CABG patients.
Methods:
A systematic review of original studies, observational studies, systematic reviews, meta-analyses, case studies, and case series was conducted using PubMed, Web of Science, Scopus, EMBASE, and Google Scholar involving adult patients (>18) with SVGA after CABG using MESH terminology in a broad search strategy. All searches were performed and analyzed according to PRISMA and duplicates were removed via Rayyan. Two independent investigators extracted and assessed the data involving demographics, and baseline data related to CABG and its manifestations.
Results:
Out of 487 finalized articles, 14 of them matched the inclusion requirements and reported 12 cases of SVGAs following CABG. Atherosclerosis with intimal calcification was the most common risk factor followed by infection. Others included hyperlipidemia, pneumonia, and cardiac pathologies mostly related to the ventricles and valves.
Conclusion:
Atherosclerosis associated with intimal calcification is the most common risk factor. Patient outcomes seem to improve upon early identification and regular follow-up imaging. The exclusion criteria indicated the study's limits, and future studies that address these constraints may be able to better understand the risk variables involved in the genesis of SVGA.
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