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Updated: May 24, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
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A modified scleroderma skin scoring method.

M B Kahaleh, G L Sultany, E A Smith

    Clinical and Experimental Rheumatology
    |October 1, 1986
    PubMed
    Summary
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    Skin thickness in scleroderma correlates with internal organ involvement. A new objective skin scoring method shows good reproducibility for monitoring disease activity in scleroderma patients.

    Area of Science:

    • Rheumatology
    • Dermatology
    • Medical Diagnostics

    Background:

    • Skin thickness in scleroderma is linked to internal organ involvement.
    • Objective assessment of skin involvement is needed for disease management.

    Purpose of the Study:

    • To describe and evaluate an objective method for assessing skin involvement in scleroderma.
    • To determine the inter-observer reproducibility of this new skin scoring method.

    Main Methods:

    • A preliminary study involving twenty scleroderma patients.
    • Development and testing of an objective clinical evaluation method for skin involvement (skin score).

    Main Results:

    • The proposed skin scoring method demonstrated an acceptable degree of inter-observer reproducibility.

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  • The method provides an objective measure for evaluating skin changes in scleroderma.

    • Conclusions:

    • The objective skin score is a reliable tool for assessing skin involvement in scleroderma.
    • This method can be utilized for monitoring disease progression and overall activity in scleroderma patients.