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Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

35
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

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Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
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Microorganisms in Agriculture and Food industry01:27

Microorganisms in Agriculture and Food industry

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Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
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Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

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Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
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Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

29
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
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Anatomy of the Intestines01:23

Anatomy of the Intestines

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Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
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Related Experiment Video

Updated: Jul 11, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

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[Microbiome: from pathophysiology to clinical application?]

Michael Scharl1, Gerhard Rogler1

  • 1Klinik für Gastroenterologie und Hepatologie, UniversitätsSpital Zürich, Zürich, Switzerland.

Deutsche Medizinische Wochenschrift (1946)
|November 2, 2023
PubMed
Summary
This summary is machine-generated.

The intestinal microbiota, or microbiome, is crucial in disease. Standardized microbiome therapies are now available, complementing fecal microbiota transplantation for clinical use.

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Area of Science:

  • Microbiology and Immunology
  • Gastroenterology

Context:

  • The microbiome, specifically the intestinal microbiota, is a rapidly growing area of scientific research.
  • Over 25,000 publications emerge annually, highlighting its increasing importance.
  • Research focuses on the microbiome's role in disease pathophysiology.

Purpose:

  • To provide an overview of key developments in microbiome research.
  • To highlight the emergence of standardized microbiome therapeutics.

Summary:

  • The U.S. Food and Drug Administration (FDA) has approved or is nearing approval for the first microbiome-based therapies.
  • These standardized products offer an alternative to fecal microbiota transplantation (FMT).
  • These advancements are integrating microbiome interventions into clinical practice.

Impact:

  • Establishes a new class of therapeutic options for conditions like *Clostridioides difficile* colitis.
  • Facilitates the clinical application of microbiome science.
  • Represents a significant step forward in harnessing the microbiome for health.