Effect of Real-Time Computer-Aided Polyp Detection System (ENDO-AID) on Adenoma Detection in...

Area of Science:

• Gastroenterology
• Medical Technology
• Clinical Trials

Background:

• The impact of computer-aided polyp detection (CADe) on adenoma detection rate (ADR) among endoscopists-in-training is not well-established.
• Colonoscopy is a key procedure for colorectal cancer screening and diagnosis.

Purpose of the Study:

• To evaluate the effectiveness of CADe in improving ADR in endoscopists with limited experience.
• To assess the influence of CADe on the detection of adenomas of different sizes and locations.

Main Methods:

• A single-blind, parallel-group, randomized controlled trial was conducted with 766 participants undergoing colonoscopy.
• Endoscopists-in-training were randomized to use CADe (ENDO-AID[OIP-1]) or not (control) during withdrawal.
• Primary outcome was the adenoma detection rate (ADR); secondary outcomes included ADR by adenoma size/location and non-neoplastic polyp resection rate.

Main Results:

• The overall ADR was significantly higher in the CADe group (57.5%) compared to the control group (44.5%).
• CADe use led to higher ADR for small (<5 mm) and medium (5-10 mm) adenomas, and in both the right and left colon.
• The mean number of adenomas detected and the non-neoplastic resection rate were also significantly higher in the CADe group.

Conclusions:

• Computer-aided polyp detection (CADe) significantly increases the adenoma detection rate (ADR) in endoscopists-in-training.
• The study demonstrates the value of CADe in enhancing colonoscopic surveillance and potentially improving patient outcomes.