Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

22.0K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
22.0K
The DNA Helix01:07

The DNA Helix

20.8K
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
20.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Throughput Monitoring of Electrochemical Reactions on Single Nanoparticles via Fourier Transform Wide-Field Electrochemical Hyperspectral Imaging.

ACS nano·2026
Same author

Metal-Phenolic Coatings Enable Universal Design of Spherical Nucleic Acids.

Angewandte Chemie (International ed. in English)·2026
Same author

Programmed synthesis of mesoporous protein crystals in cellular reactors.

Nature nanotechnology·2026
Same author

Correction to "DNA-Mediated Cellular Delivery of Functional Enzymes".

Journal of the American Chemical Society·2026
Same author

Author Correction: De novo design of quasisymmetric two-component protein cages.

Nature·2026
Same author

High-χ Block Copolymer Nanoreactors for the Confined Synthesis of Size-Controlled Nanoclusters.

ACS nano·2026
Same journal

Intranasal DNA nanocarrier vaccines with surface-patterned antigens enhance efficacy against respiratory syncytial virus.

Nature materials·2026
Same journal

An artificial neuromorphic interface for auditory restoration.

Nature materials·2026
Same journal

Seamless biointerfaces in devices.

Nature materials·2026
Same journal

Shaping the future of quantum technology.

Nature materials·2026
Same journal

Quantum tunnelling and leakage current across two-dimensional materials.

Nature materials·2026
Same journal

High-precision memristor-based computing.

Nature materials·2026
See all related articles

Related Experiment Video

Updated: Jul 11, 2025

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

11.7K

Colloidal quasicrystals engineered with DNA.

Wenjie Zhou1,2, Yein Lim3, Haixin Lin1,2

  • 1International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA.

Nature Materials
|November 3, 2023
PubMed
Summary
This summary is machine-generated.

Scientists engineered colloidal quasicrystals using DNA-programmed nanoscale decahedra. This breakthrough enables the rational design of programmable matter by controlling particle assembly through DNA interactions.

More Related Videos

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
08:02

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures

Published on: May 31, 2024

802
Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.5K

Related Experiment Videos

Last Updated: Jul 11, 2025

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

11.7K
Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
08:02

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures

Published on: May 31, 2024

802
Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.5K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biophysics

Background:

  • Designing synthetic colloidal crystals is generally feasible.
  • However, the rational assembly of colloidal quasicrystals remains a significant challenge in materials science.

Purpose of the Study:

  • To develop a method for the deliberate and rational formation of colloidal quasicrystals.
  • To demonstrate the use of nanoscale decahedra with DNA functionalization for programmable self-assembly.

Main Methods:

  • Utilized nanoscale decahedra with DNA strands immobilized on their facets.
  • Exploited the geometry of decahedra and DNA bonding for enthalpy-driven assembly.
  • Leveraged energetic preferences for DNA duplex formation and facet alignment.

Main Results:

  • Successfully assembled colloidal quasicrystals with defined axial structures.
  • Observed local five- and six-coordinated motifs, square-triangle tiling with rhombus defects.
  • Achieved quasiperiodic layers with stacking disorder, ensuring thermodynamic stability.

Conclusions:

  • Established a novel engineering approach for creating colloidal quasicrystals.
  • Demonstrated a significant advancement in the deliberate design of programmable matter.
  • The method is versatile, applicable across various particle sizes and DNA lengths.