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Clinical Characteristics and Outcomes of COVID-19 Patients in Mazandaran Province, Iran

Faezeh Sadat Movahedi1, Jamshid Yazdani Charati2, Farhang Baba Mahmoudi3

  • 1Student Research Committee, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.

Tanaffos
|November 3, 2023
PubMed

Insights

Older age, intubation, low oxygen saturation, and comorbidities like cancer, heart failure, and kidney disease significantly increase COVID-19 fatality risk. Identifying these factors aids early prognosis and targeted medical care for better patient outcomes.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • Coronaviruses, including COVID-19, pose a significant global health challenge.
  • Understanding clinical characteristics and risk factors for severe outcomes is crucial for effective management.
  • This study focuses on COVID-19 patients in Mazandaran province.

Purpose of the Study:

  • To investigate and describe the clinical characteristics of COVID-19 patients.
  • To identify risk factors associated with fatality rate in COVID-19 patients.
  • To analyze the length of hospital stay for COVID-19 patients.

Main Methods:

  • An epidemiological study analyzing data from hospitalized COVID-19 patients.
  • Data collected from July 22 to August 21, 2020, in Mazandaran province.
  • Multivariate logistic regression and Cox proportional hazards models used to determine fatality risk factors.

Main Results:

  • Out of 6759 patients, 46.03% had comorbidities (diabetes, hypertension, heart failure).
  • Key fatality risk factors identified: age over 60 (HR: 1.93), intubation (HR: 4.22), SpO2 ≤ 93% (HR: 2.57).
  • Other significant risk factors included cancer (HR: 1.87), chronic blood diseases (HR: 1.83), heart failure (HR: 1.63), and chronic kidney disease (HR: 1.98).

Conclusions:

  • Early identification of high-risk patients based on identified factors can improve prognosis.
  • Further research is needed to understand the underlying mechanisms of these risk factors.
  • Highlighting death-related risk factors is essential for enhancing preparedness and medical interventions.
Abstract

Keywords:
COVID-19Cox regressionOutcome

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