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Updated: Jul 11, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
What generative AI means for trust in health communications
Adam G Dunn1, Ivy Shih2, Julie Ayre3
1Faculty of Medicine and Health, Biomedical Informatics and Digital Health, School of Medical Sciences, The University of Sydney, Sydney, Australia.
Abstract:
ABSTRACTLarge language models are fundamental technologies used in interfaces like ChatGPT and are poised to change the way people access and make sense of health information. The speed of uptake and investment suggests that these will be transformative technologies, but it is not yet clear what the implications might be for health communications. In this viewpoint, we draw on research about the adoption of new information technologies to focus on the ways that generative artificial intelligence (AI) tools like large language models might change how health information is produced, what health information people see, how marketing and misinformation might be mixed with evidence, and what people trust. We conclude that transparency and explainability in this space must be carefully considered to avoid unanticipated consequences.
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