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Updated: Jul 11, 2025
Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
Published on: September 22, 2015
Advances in volumetric bioprinting
Sibo Jing1, Liming Lian2, Yingying Hou1
1The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou 511436, People's Republic of China.
Volumetric bioprinting (VBP) overcomes slow printing speeds in biofabrication, enabling rapid creation of complex, centimeter-scale tissue constructs. This technology advances tissue engineering, regenerative medicine, and drug testing applications.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Additive Manufacturing
Background:
- Three-dimensional (3D) bioprinting offers high precision for biomedical applications.
- Current layer-by-layer bioprinting methods are limited by slow fabrication speeds.
- This limitation hinders the large-scale production of complex tissue constructs.
Purpose of the Study:
- To introduce volumetric bioprinting (VBP) as a solution to slow bioprinting speeds.
- To review VBP principles, hardware, and recent advancements in bioinks.
- To discuss the biomedical applications and future directions of VBP.
Main Methods:
- Review of volumetric bioprinting (VBP) principles and hardware designs.
- Focus on recent advances in VBP-based bioinks.
- Analysis of VBP's biomedical applications and limitations.
Main Results:
- VBP enables the rapid creation of geometrically complex, centimeter-scale constructs in seconds.
- VBP represents a significant advancement over sequential biofabrication methods.
- VBP opens new possibilities for tissue engineering, regenerative medicine, drug testing, and soft robotics.
Conclusions:
- VBP is a promising technology for accelerating biofabrication.
- Further research into VBP bioinks and applications is warranted.
- VBP has the potential to revolutionize personalized medicine and tissue regeneration.
