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Updated: Jul 11, 2025

Murine Fecal Isolation and Microbiota Transplantation
Published on: May 26, 2023
Unveiling the relationship between gut microbiota and heart failure: Recent understandings and insights
Hritvik Jain1, Mohammed Dheyaa Marsool Marsool2, Aman Goyal3
1Department of Internal Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, India.
Abstract:
Gut microbiota, which comprises a broad range of bacteria inhabiting the human intestines, plays a crucial role in establishing a mutually beneficial relationship with the host body. Dysbiosis refers to the perturbations in the composition or functioning of the microbial community, which can result in a shift from a balanced microbiota to an impaired state. This alteration has the potential to contribute to the development of chronic systemic inflammation. Heart failure (HF) is a largely prevalent clinical condition that has been demonstrated to have variations in the gut microbiome, indicating a potential active involvement in the pathogenesis and advancement of the disease. The exploration of the complex interplay between the gut microbiome and HF presents a potential avenue for the discovery of innovative biomarkers, preventive measures, and therapeutic targets. This review aims to investigate the impact of gut bacteria on HF.
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