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Related Concept Videos

Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

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Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
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Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

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Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
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Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

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Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
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Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

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Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: Jul 11, 2025

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Unilateral non-healing ulcers in zosteriform pattern.

Sanjiv Choudhary1, Ankita Srivastava2, Prerna Nagi2

  • 1Dermatology, All India Institute of Medical Sciences, Nagpur, Maharashtra, India sanjiv.derma26@gmail.com.

BMJ Case Reports
|November 3, 2023
PubMed
Summary

Trigeminal trophic syndrome (TTS), a rare condition from trigeminal nerve injury, presents as facial ulcers and sensory loss. This case highlights TTS as a complication of herpes zoster, likely due to varicella-zoster virus nerve damage.

Area of Science:

  • Neurology
  • Dermatology
  • Infectious Diseases
Keywords:
DermatologyGeneral practice / family medicineNeurology

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Background:

  • Trigeminal trophic syndrome (TTS) is a rare disorder characterized by facial ulceration and sensory disturbances following trigeminal nerve injury.
  • First described in the early 20th century, approximately 200 cases of TTS have been reported globally.
  • The condition typically manifests as persistent, non-healing ulcers accompanied by hypoesthesia and paresthesia within the trigeminal nerve distribution.