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Autologous fat injection for empty-nose syndrome
1Service d'ORL et de Chirurgie Cervicofaciale, Centre Hospitalier de Valence, 179, boulevard du Maréchal-Juin, 26953 Valence, France.
European Annals of Otorhinolaryngology, Head and Neck Diseases
|November 4, 2023
Summary
Autologous fat injection offers a promising minimally invasive treatment for empty nose syndrome (ENS), improving symptoms for most patients. While not a complete cure, this technique shows potential for managing ENS without complications.
Area of Science:
- Otolaryngology
- Rhinology
- Plastic Surgery
Background:
- Empty nose syndrome (ENS) presents a therapeutic challenge, with limited evidence supporting current treatments like inferior turbinate augmentation.
- Minimally invasive techniques are sought to manage ENS symptoms effectively.
Purpose of the Study:
- To evaluate the efficacy of autologous fat injection for inferior meatus augmentation in patients with ENS.
- To assess changes in Empty Nose Syndrome 6-item Questionnaire (ENS6Q) scores and identify any complications.
Main Methods:
- A cohort of 11 patients with ENS underwent autologous fat injection between March 2021 and December 2022.
- The primary outcome measure was the change in overall ENS6Q scores.
- Secondary outcomes included analysis of individual ENS6Q items and complication monitoring.
Main Results:
- Ten out of eleven patients demonstrated a significant reduction in overall ENS6Q scores (P=0.0058).
- Six patients achieved a final ENS6Q score below 11, indicating symptom improvement.
- Patient satisfaction was high (10/11), though residual symptoms persisted. No complications were reported.
Conclusions:
- Autologous fat injection appears to be an effective and safe method for improving ENS symptomatology, corroborating existing literature.
- While beneficial, this approach does not fully resolve all symptoms, necessitating further research.
- Larger, multicenter studies with extended follow-up are required to validate these findings.
