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Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Dysrhythmias III: Characteristics of Dysrhythmias01:29

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Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
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Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

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Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
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Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

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Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Pulse rhythm01:30

Pulse rhythm

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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC). Part 2-Cardiovascular Magnetic Resonance, Cardiac CT and Nuclear Imaging.

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Related Experiment Video

Updated: Jul 11, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Exploring the Temporal Patterns of Right Ventricular Pacing Burden.

Rahul K Chattopadhyay1,2, Mrinal Thakur1, Rucchira Wickramasinghe1

  • 1Department of Cardiology, Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

The Journal of Innovations in Cardiac Rhythm Management
|November 6, 2023
PubMed
Summary
This summary is machine-generated.

Right ventricular pacing (RVP) burden did not significantly change over time across various indications. However, patients with sinus node disease and prolonged PR intervals showed higher RVP burdens.

Keywords:
Conduction system pacingpacing-induced cardiomyopathyright ventricular pacing burden

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Device Technology

Background:

  • Elevated right ventricular pacing (RVP) burdens are linked to pacing-induced cardiomyopathy.
  • Current European and American pacing guidelines consider anticipated pacing burden for conduction system pacing indications.
  • Understanding temporal RVP burden patterns is crucial for predicting future needs and selecting optimal pacing modalities.

Purpose of the Study:

  • To investigate the temporal changes in RVP burden across different pacing indications.
  • To identify factors influencing RVP burden over time.
  • This is the first study to assess the evolution of RVP burden in relation to pacing indications.

Main Methods:

  • Retrospective, single-center, observational study design.
  • Extraction of RVP burden data from pacing checks.
  • Plotting RVP burdens against 6-month time bins for graphical analysis.

Main Results:

  • No significant temporal change in RVP burden was observed, irrespective of the initial pacing indication.
  • Individuals with sinus node disease (SND) and a P-R interval >250 ms demonstrated increased RVP burden.
  • Most patients, excluding those with SND and a P-R interval <250 ms, exhibited pacing burdens exceeding guideline recommendations for conduction system pacing.

Conclusions:

  • RVP burden remains relatively stable over time for most patients.
  • Specific patient subgroups, such as those with SND and prolonged PR intervals, may experience higher RVP burdens.
  • Current pacing practices may lead to higher-than-recommended pacing burdens in many patients, highlighting potential areas for guideline adherence and modality selection review.