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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Atrial Fibrillation Ablation in Patients With Chronic Kidney Disease: A Review of Literature

Arjun Basnet1, Azka Naeem1, Nava R Sharma2

  • 1Internal Medicine, Maimonides Medical Center, Brooklyn, USA.

Cureus
|November 6, 2023
PubMed

Insights

Catheter ablation (CA) is a safe and effective treatment for atrial fibrillation (AF) in chronic kidney disease (CKD) patients, offering benefits over anti-arrhythmic drugs. While CKD patients face higher heart failure hospitalization risks post-ablation, CA may improve kidney function.

Area of Science:

  • Nephrology
  • Cardiology
  • Electrophysiology

Background:

  • Atrial fibrillation (AF) is prevalent in chronic kidney disease (CKD) patients, increasing cardiovascular risks.
  • Catheter ablation (CA) is a potential treatment for AF in CKD, but its safety and efficacy require further investigation.
  • CKD complicates AF management, necessitating tailored therapeutic strategies.

Purpose of the Study:

  • To evaluate the safety and effectiveness of catheter ablation (CA) for atrial fibrillation (AF) in patients with chronic kidney disease (CKD).
  • To compare outcomes of CA in CKD patients versus non-CKD patients.
  • To explore the impact of CA on kidney function in CKD patients with AF.

Main Methods:

  • Retrospective analysis of CKD patients undergoing CA for AF.
  • Comparison of complication rates, hospitalization, and adverse events between CKD and non-CKD patient cohorts.
  • Assessment of changes in kidney function parameters post-CA in CKD patients maintaining sinus rhythm.

Main Results:

  • Catheter ablation (CA) is a safe and effective treatment for atrial fibrillation (AF) in chronic kidney disease (CKD) patients.
  • CKD patients undergoing CA experienced similar complication rates to non-CKD patients but had a higher risk of heart failure hospitalization.
  • CA demonstrated potential benefits for kidney function in CKD patients who maintained sinus rhythm post-procedure.

Conclusions:

  • Catheter ablation (CA) offers a viable and safer alternative to anti-arrhythmic drugs for managing atrial fibrillation (AF) in chronic kidney disease (CKD) patients.
  • While CKD patients face specific risks like heart failure hospitalization after CA, the procedure shows promise for renal function improvement.
  • Future research should focus on advanced CKD populations, long-term outcomes, and personalized treatment strategies for AF ablation in CKD.

Keywords:
atrial fib ablationatrial fibrillation ablationatrial fibrillation recurrencechronic kidney disease (ckd)radio-frequency ablation

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