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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
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Electroacupuncture for ulcerative colitis patients: A meta-analysis and acupoints selection study.

Jianheng Hao1,2, Yuemeng Zhao1, Yuxia Cao2

  • 1College of Acupuncture and Massage, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

Heliyon
|November 6, 2023
PubMed
Summary

Electroacupuncture (EA) significantly improves clinical efficacy and cure rates for ulcerative colitis (UC). Optimal treatment involves specific acupoints and dense wave stimulation for over six weeks.

Keywords:
AcupointsElectroacupuncture(EA)MeridiansMeta-analysisUlcerative colitis(UC)

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Area of Science:

  • Integrative Medicine
  • Gastroenterology
  • Acupuncture Research

Background:

  • Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited treatment options.
  • Electroacupuncture (EA) is a therapeutic technique in Traditional Chinese Medicine (TCM) with potential anti-inflammatory effects.
  • Optimizing EA parameters and acupoint selection is crucial for maximizing its therapeutic benefits in UC.

Purpose of the Study:

  • To evaluate the efficacy and safety of electroacupuncture (EA) for treating ulcerative colitis (UC).
  • To explore how EA parameters and acupoint combinations influence treatment outcomes.
  • To optimize clinical treatment plans for UC using EA.

Main Methods:

  • A systematic literature search was conducted across eight databases.
  • Data from randomized controlled trials (RCTs) were extracted and analyzed for quality and bias.
  • A meta-analysis was performed on the collected RCT data.

Main Results:

  • Twelve studies were included in the meta-analysis.
  • EA demonstrated significantly better clinical efficacy (RR=1.27, P<0.01) compared to control groups.
  • Improvements were observed in cure rate (RR=1.73, P<0.01), mucosal lesion healing (RR=1.24, P<0.01), and reduced TNF-α levels (MD=-41.11, P<0.01).

Conclusions:

  • EA shows superior clinical efficacy and curative effects for UC, including improvements in mucosal healing, inflammatory markers, and TCM syndrome scores.
  • Optimal EA treatment for UC may involve acupoints from the Bladder, Stomach, and Ren meridians.
  • Dense wave stimulation for 30 minutes, more than 6 weeks, is suggested as an optimal treatment protocol.