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Murine Full-thickness Skin Transplantation
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Gorham-Stout disease: remission with sirolimus therapy

Stefanie W Y Yip1, James F Griffith1, Cina S L Tong1

  • 1Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.

BJR Case Reports
|November 6, 2023
PubMed
Summary

Gorham-Stout disease (GSD) is a rare bone disorder. Sirolimus effectively treated a patient with GSD, showing near-complete resolution after one year, unlike propranolol.

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Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
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