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Rapid characterization of anti-CRISPR proteins and optogenetically engineered variants using a versatile plasmid

Guoxu Song1,2, Chunhong Tian1,2,3, Jiahui Li1,2,3

  • 1Key Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Nucleic Acids Research
|November 6, 2023
PubMed
Summary

Researchers developed a new system to quickly find anti-CRISPR (Acr) proteins and create controllable CRISPR tools. This system led to the discovery of new Acrs and light-activated Cas9 control systems for genome editing.

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