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Bile duct hamartoma in a dog
Dongsheng Mao1, Xudong Song2, Dexing Ma2
1State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 678 Haping Road, Xiangfang District, Harbin, 150001, China.
Journal of Comparative Pathology
|November 6, 2023
Summary
A rare bile duct hamartoma was diagnosed in a dog, presenting as a large liver mass causing abdominal distension. This is the first documented case of this specific liver tumor in canine veterinary medicine.
Area of Science:
- Veterinary Pathology
- Canine Oncology
- Hepatobiliary Diseases
Background:
- Liver masses are common in dogs, but bile duct hamartomas are exceptionally rare.
- This case highlights the importance of thorough histopathological and immunohistochemical analysis for accurate diagnosis of canine liver tumors.
Observation:
- An 11-year-old Collie presented with marked abdominal enlargement due to a large liver mass.
- Computed tomography confirmed a significant mass in the left lateral liver lobe.
- Surgical excision was performed via laparotomy.
Findings:
- Histopathology revealed numerous small, dilated, anastomosing cystic structures forming a net-like pattern.
- Immunohistochemistry confirmed the presence of bile duct structures (cytokeratin 19-positive) within the cystic lumens.
- The tumor was definitively diagnosed as a bile duct hamartoma.
Implications:
- This case represents the first reported instance of a bile duct hamartoma in a dog.
- Accurate diagnosis of rare liver tumors is crucial for appropriate treatment and prognosis in canine patients.
- Further research may elucidate the specific etiology and behavior of bile duct hamartomas in canines.
