Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and safety of ofatumumab in participants with relapsing multiple sclerosis and breakthrough disease on oral fingolimod or fumarates: results from the ARTIOS study.

Journal of neurology·2026
Same author

Turkish adaptation and psychometric testing of the Perceived Workplace Support Scale in people with inflammatory arthritis.

Rheumatology advances in practice·2026
Same author

Summary of Research: Cognition and Employment Status of People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Two-Year CLARIFY-MS Study.

Neurology and therapy·2026
Same author

Correction: Stability in Cognition and Employment in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Two‑year Phase IV CLARIFY‑MS Study.

Neurology and therapy·2026
Same author

Comparative impact of mental and cardiovascular comorbidities on adverse outcomes in people with MS.

Journal of the neurological sciences·2026
Same author

The association between prescribed hormonal contraception and multiple sclerosis risk: a systematic review and meta-analysis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026

Related Experiment Video

Updated: Jul 11, 2025

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.0K

Multiple Sclerosis vision questionnaire (MSVQ-7): Reliability, validity, precision and discrimination.

Carolyn A Young1, David J Rog2, Radu Tanasescu3

  • 1Molecular and Integrative Biology, Institute of Systems, University of Liverpool, Liverpool, United Kingdom; Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.

Multiple Sclerosis and Related Disorders
|November 6, 2023
PubMed
Summary
This summary is machine-generated.

The MS Vision Questionnaire (MSVQ-7) is a reliable tool for assessing vision problems in people with Multiple Sclerosis (pwMS). It shows significant changes over time and strongly correlates with depression and stigma.

Keywords:
DepressionMSVQ-7RaschTrajectories of Outcome in Neurological Conditions-MSVision

More Related Videos

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.1K
A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision
09:29

A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision

Published on: February 11, 2014

13.1K

Related Experiment Videos

Last Updated: Jul 11, 2025

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.0K
Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.1K
A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision
09:29

A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision

Published on: February 11, 2014

13.1K

Area of Science:

  • Ophthalmology
  • Neurology
  • Psychometrics

Background:

  • Visual dysfunction is a prevalent and complex issue for people with Multiple Sclerosis (pwMS).
  • Existing methods for capturing the patient experience of visual pathology are challenging.
  • A validated, reliable patient-reported measure is needed for clinical and research benefits.

Purpose of the Study:

  • To examine the psychometric properties of the MS Vision Questionnaire (MSVQ-7) in a large Multiple Sclerosis (MS) population.
  • To assess the MSVQ-7's ability to detect clinically significant changes in visual problems over time.
  • To explore the relationship between visual dysfunction and other factors like depression, anxiety, and stigma in pwMS.

Main Methods:

  • Utilized data from the UK-wide Trajectories of Outcome in Neurological Conditions-MS (TONiC-MS) study.
  • Performed Confirmatory Factor Analysis and Rasch analysis on a calibration sample of 1000 pwMS.
  • Calculated Minimal Detectable Change (MDC) and Minimal Clinically Important Change (MIC) using an anchor-based method.

Main Results:

  • The MSVQ-7 demonstrated unidimensionality and fit the Rasch model, allowing conversion to an interval-level metric.
  • 80% of 5478 pwMS reported visual problems, with scores varying by MS subtype and changing over time.
  • Clinically significant changes in MSVQ-7 scores were reported by over a quarter of the follow-up sample; vision issues strongly predicted depression risk.

Conclusions:

  • The MSVQ-7 is a precise and discriminating brief self-report measure for visual problems in pwMS.
  • Visual problems are common, change over time, and significantly impact depression risk and stigma.
  • The MSVQ-7 exhibits strong psychometric properties, supporting its adoption in clinical and research settings for routine visual assessment.