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Updated: Jul 11, 2025

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Sarcoid optic neuropathy
Pedro Fraiman1, André Lopes Valente1, Maria Eduarda Slhsessarenko Fraife Barreto1
1Division of General Neurology and Ataxia Unit, Department of Neurology and Neurosurgery, UNIFESP, Sao Paulo, Brazil.
Abstract:
A 45-year-old woman presented with sudden complete vision loss in her left eye and retroorbital pain worsened by eye movements. A previous milder episode of vision loss had occurred in the same eye 1 year before, with complete recovery after high-dose intravenous methylprednisolone. She had no light perception in the left eye with a swollen optic disc, but with a normal right optic disc. There were no systemic manifestations or infections. MR scan of the brain showed extensive enlargement and enhancement of the left optic nerve and optic chiasm. After excluding infections and autoimmune markers, a left optic nerve biopsy confirmed non-caseating granulomas, leading to a diagnosis of neurosarcoidosis.
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