Related Experiment Video

Updated: Jul 11, 2025

Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
07:56

Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis

Published on: May 5, 2023

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[Preliminary progress in the study of the relationship between COVID-19 infection and partial arterial or venous

L X Ren1, M W Wu1, J Xiong1

  • 1Department of Vascular and Endovascular Surgery, the First Medical Center of Chinese People's Liberation Army General Hospital,Beijing 100853,China.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|November 6, 2023
PubMed

Insights

COVID-19 infection is linked to serious vascular issues, including aortic diseases and venous thromboembolic diseases like deep vein thrombosis and pulmonary embolism. This review explores potential causes and prevention strategies for these critical COVID-19-related vascular complications.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Vascular Surgery

Background:

  • COVID-19 infection is increasingly recognized for its association with diverse vascular complications.
  • Reports highlight a strong link between COVID-19 and venous thromboembolic diseases (VTE), such as deep vein thrombosis (DVT) and pulmonary embolism (PE).
  • COVID-19 has also been implicated in various aortic pathologies, including aortic valve stenosis, aortic thrombosis, abdominal aortic aneurysm (AAA), aortic dissection, and limb ischemia.

Approach:

  • This article presents a comprehensive review of aortic diseases and VTE associated with COVID-19.
  • It aims to elucidate the potential underlying mechanisms contributing to these vascular conditions in COVID-19 patients.
  • Strategies for thrombosis prevention in the context of COVID-19 are discussed.

Key Points:

  • Vascular complications are a significant concern in COVID-19 patients.
  • Understanding the pathogenesis of COVID-19-associated vascular diseases is crucial for effective management.
  • Proactive thrombosis prevention is a critical component of comprehensive care for these patients.

Conclusions:

  • The association between COVID-19 and vascular complications, including VTE and aortic diseases, necessitates further investigation.
  • Identifying causative mechanisms will guide the development of targeted therapeutic and preventive strategies.
  • Effective management of COVID-19 requires a multidisciplinary approach addressing its vascular sequelae.

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