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Updated: Jul 11, 2025
05:54
Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
Published on: June 13, 2016
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Comprehensive Outcome Assessment and Quality of Life Following Epilepsy Surgery
Garima Shukla1,2, Neha Nandal1,3, Mohammed Afsar1,4
1Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Summary
Epilepsy surgery aims for seizure freedom, but co-morbidities like mood and social issues impact quality of life (QOL). Impaired memory, depression, and social stigma significantly affect QOL even in seizure-free patients.
Area of Science:
- Neurology
- Neurosurgery
- Psychiatry
Background:
- Epilepsy surgery aims for seizure freedom without neurological deficits.
- Medically refractory epilepsy patients often experience mood, cognitive, sleep, and social co-morbidities.
- Limited research exists on non-seizure outcomes and their impact on quality of life (QOL) post-surgery.
Purpose of the Study:
- To investigate the influence of non-seizure parameters on post-epilepsy surgery QOL.
- To identify specific co-morbidities and social factors affecting patient outcomes.
Main Methods:
- Adult patients with refractory epilepsy, operated at least 1 year prior, were assessed.
- Patients were categorized as seizure-free (group 1) or non-seizure-free (group 2).
- Quality of life (QOL) was measured using the QOLIE-31 instrument; non-seizure factors included cognition, mood, social aspects, and sleep.
Main Results:
- Among seizure-free patients (group 1), impaired memory, lower language scores, depression, unemployment, lack of prior education, and social stigma were linked to poor QOL.
- All patients in the non-seizure-free group (group 2) reported poor QOL.
Conclusions:
- Non-seizure factors, including co-morbidities and social issues, are prevalent in seizure-free epilepsy surgery patients with poor QOL.
- Addressing these factors is crucial for improving overall patient outcomes after epilepsy surgery.
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